Advel 400

৳ 1.44

Advel 400 400 mg Tablet

Advel 400 400 mg Tablet

Indication: pain and inflammation in rheumatic diseases including juvenile chronic arthritis (JCA) and other musculoskeletal disorders; mild to moderate pain including dysmenorrhoea; fever and pain in children
Cautions: Should be used with caution in the elderly, in allergic disorders, during pregnancy and breast feeding, and in coagulative defects. In patients with renal, hepatic or cardiac impairment caution is required since the use of NSAIDs may result in deterioration of renal function.

Contraindications: Contraindicated in patients with active peptic ulceration, Crohn’s disease or ulcerative colitis. They should be avoided in patients with previous gastrointestinal bleeding or ulceration, and should be withdrawn if gastro-intestinal lesions develop.They are also contra-indicated in patients with a history of hypersensitivity to any other NSAIDs – which include asthma, angio-oedema, urticaria or rhinitis.

Side effects: Gastro-intestinal discomforts, diarrhoea, and occasionally bleeding and ulceration occur. Taking these drugs with food or milk may minimize dyspepsia. Concomitant use of ranitidine or any other H2 blocker is strongly recommended to counteract or minimize dyspepsia. Other side effects include hypersensitivity reactions (particularly rashes, bronchospasm and angioedema), headache, dizziness, vertigo, tinnitus, photosensitivity and haematuria. Blood disorders have also occurred.

Dose: 1.2 to 1.6 g daily in 3-4 divided doses preferably after food; maximum dose permitted is 2.4 g daily; maintenance dose of 0.6-1.2 g daily may be adequate. CHILD 20 mg/kg daily in divided doses; maximal dose allowed is 40 mg/kg; not recommended for children under 7 kg