Apain TR 100

৳ 3.01

Apain TR 100 100 mg Capsule

Apain TR 100 100 mg Capsule

Indications: acute post-traumatic mus-culoskeletal pain, rheumatoid arthritis (including JCA), advanced osteoarthritis, acute gout, dysmenorrhoea, and post-operative pain
Cautions: Should be used with caution in the elderly, in allergic disorders, during pregnancy and breast feeding, and in coagulative defects. In patients with renal, hepatic or cardiac impairment caution is required since the use of NSAIDs may result in deterioration of renal function.

Contraindications: Contraindicated in patients with active peptic ulceration, Crohn’s disease or ulcerative colitis. They should be avoided in patients with previous gastrointestinal bleeding or ulceration, and should be withdrawn if gastro-intestinal lesions develop.They are also contra-indicated in patients with a history of hypersensitivity to any other NSAIDs – which include asthma, angio-oedema, urticaria or rhinitis.

Side effects: Gastro-intestinal discomforts, diarrhoea, and occasionally bleeding and ulceration occur. Taking these drugs with food or milk may minimize dyspepsia. Concomitant use of ranitidine or any other H2 blocker is strongly recommended to counteract or minimize dyspepsia. Other side effects include hypersensitivity reactions (particularly rashes, bronchospasm and angioedema), headache, dizziness, vertigo, tinnitus, photosensitivity and haematuria. Blood disorders have also occurred.

Dose:by mouth, 75-150 mg in 2 to 3 divided doses, preferably after meals. Dispersible preparations may be taken dissolved in water for rapid control of pain (for short period only). Slow release (SR) preparations, 100 mg once daily after meals (for management of chronic painful or inflammatory conditions)
By rectum in suppositories, 50 mg once to thrice a daily
By injections, 75 mg once or twice daily by IM injections into gluteal muscles for not more than 3 days. IV injections can be administered (in hospital settings, for post operative pain relief), 75 mg dissolved in 100 ml Normal Saline by slow infusion over 60 minutes, repeated in 4 to 6 hours if necessary
Maximum total daily dose by any or a combination of routes is 150 mg
CHILD 1-12 years, for JCA, can be given by mouth or by rectum 1-3 mg/kg daily in divided doses (as 25 mg tablets or 12.5 mg suppositories)